BIOACTIVE MICROBIAL METABOLITES
Microorganisms and their metabolites have major impact on our daily lives. The goal of the research core facility Bioactive Microbial Metabolites (BiMM), is to isolate new and active substances and enzymes from fungi and bacteria and to provide infrastructure for high throughput screenings.
The BiMM facility is an open research platform. The facility provides hardware and expertise for cooperation projects and contract work. The BiMM with robotic liquid handling equipment is especially adapted to perform high throughput searches for bioactive metabolites and enzymes. We further characterize the chemical and biological properties of the found substances.
Metabolite identification is facilitated by the expertise and equipment of the Department for Agrobiotechnology and the Department of Chemistry of the University for Natural Resources (BOKU) in Tulln.
BiMM 2.0
BiMM’s successes are rewarded and the research platform continues to receive financial support from „Land Niederösterreich“.
Kurzvideo zur Forschungsplattform mit Grußworten von Landeshauptfrau Johanna Mikl-Leitner (3min, DE)
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BiMM offers an extraordinary Virtual Reality of a fungi-cell
Virtual Reality – Inside a fungal cell
(6 min, EN)
The 3D movie is impressive. But if you put on virtual reality glasses, you become a miniature yourself and find yourself in the middle of a fungal cell, surrounded by strange formations such as vacuole, golgi, mitochondria and ribosomes. The fungal researchers group of the molecular geneticist Joseph Strauss from the BOKU Institute for Microbial Genetics present a unique virtual interior view of a fungal cell.
Comments on the Virtual Reality – Inside a fungal cell
(3 min, DE, english subtitles)
A virtual reality seen through virtualreality glasses can positively change learning. Students can combine the knowledge they have gained from a complex structure (such as the fungus) with positive emotions through virtual reality. These emotions allow the learning process tobe positively controlled. Learning is always associated with emotions.“
(Alexandra Strauss-Sieberth, BOKU E-learning and didactic)
BiMM Structure
Bioactive Microbial Metabolites BiMM – Core facility
The core facility is open for co-operations with universities, research institutes, universities of applied sciences, and industry.
The BiMM infrastructure is suitable for example to …
- investigate the interaction of microbes with other organisms (bacteria, fungi, algae, plant, animal cells) and to identify the production of bioactive substances (antibiotics, pharmaceuticals, bioeffectors, agroceuticals, etc.).
- study metabolomes of microbes under a multitude of environmental and nutritional conditions to identify bio-and agro-technological potential.
- study cells of different origin (microbes, plants, insects) in their mutual stimulatory or inhibitory effects in a high-throughput way.
- study host-pathogen interactions or identify organic control species.
- screen for biotech enzymes
- perform large scale microbiology (BSL2 certified) screening experiments e.g. MIC determination
Get in contact with us: office@bimm-research.at
BiMM Bioactive Microbial Metabolites
Universitäts- & Forschungszentrum Tulln
Konrad-Lorenz-Straße 24
A-3430 Tulln
Austria
T +43 1 47654 94484